Table 6 Analysis of variance (ANOVA) results of the regression equation.

From: Preparation of curcumin submicron particles by supercritical antisolvent method with external adjustable annular gap nozzle

Parameters

Sum of squares

Degree of freedom

Mean square

F-value

P value Prob > F

Model

2.417E + 007

14

1.727E + 006

15.18

< 0.0001

A

23232.00

1

23232.00

0.20

0.6582

B

6.330E + 005

1

6.330E + 005

5.56

0.0334

C

1.118E + 006

1

1.118E + 006

9.83

0.0073

D

3.248E + 006

1

3.248E + 006

28.56

< 0.0001

AB

2.059E + 006

1

2.059E + 006

18.10

0.0008

AC

14280.25

1

14280.25

0.13

0.7284

AD

1.624E + 006

1

1.624E + 006

14.28

0.0020

BC

7.630E + 005

1

7.630E + 005

6.71

0.0214

BD

2.814E + 005

1

2.814E + 005

2.47

0.1380

CD

8.436E + 005

1

8.436E + 005

7.42

0.0165

A2

1.095E + 007

1

1.095E + 007

96.24

< 0.0001

B2

4.231E + 006

1

4.231E + 006

37.19

< 0.0001

C2

2.360E + 006

1

2.360E + 006

20.75

0.0004

D2

8.842E + 005

1

8.842E + 005

7.77

0.0145

Residual

1.592E + 006

14

1.137E + 005

  

Lack of Fit

1.491E + 006

10

1.491E + 005

5.89

0.0511

Pure Error

1.013E + 005

4

25322.80

  

SD

340.61

 

R2

 

0.9382

Mean

2206.55

 

Adj-R2

 

0.8764

C.V. %

15.44

 

Pred-R2

 

0.6605

Press

8.303E + 006

 

Adequate precision

14.060

  1. *Significance at P < 0.05.