Table 2 Associations of CVH score assessed by LE8 with the risk of Nutritional anemias and its subtype in the UK Biobank cohort study.
From: Association of life’s essential 8 and inflammatory biomarkers with nutritional anemia in UK adults
Outcomes | Ncase/Ntotal (%) | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | ||
Nutritional anemias | |||||||
Low CVH | 785/10,396 (7.6) | Reference | Reference | Reference | |||
Moderate CVH | 5359/145,361 (3.7) | 0.46 (0.43–0.50) | < 0.0001 | 0.47 (0.43–0.50) | < 0.0001 | 0.56 (0.51–0.60) | < 0.0001 |
High CVH | 605/25,312 (2.4) | 0.29 (0.26–0.33) | < 0.0001 | 0.36 (0.33–0.40) | < 0.0001 | 0.46 (0.41–0.51) | < 0.0001 |
Per 10-point increment | 6749/181,069 (3.7) | 0.73 (0.72–0.75) | < 0.0001 | 0.76 (0.74–0.78) | < 0.0001 | 0.81 (0.79–0.82) | < 0.0001 |
Iron deficiency anemia | |||||||
Low CVH | 740/10,396 (7.1) | Reference | Reference | Reference | |||
Moderate CVH | 4924/145,361 (3.4) | 0.45 (0.42–0.49) | < 0.0001 | 0.46 (0.42–0.49) | < 0.0001 | 0.54 (0.50–0.59) | < 0.0001 |
High CVH | 569/25,312 (2.2) | 0.29 (0.26–0.33) | < 0.0001 | 0.36 (0.32–0.40) | < 0.0001 | 0.46 (0.41–0.51) | < 0.0001 |
Per 10-point increment | 6233//181,069 (3.4) | 0.74 (0.72–0.75) | < 0.0001 | 0.76 (0.74–0.78) | < 0.0001 | 0.81 (0.79–0.83) | < 0.0001 |
