Table 5 Biochemical findings in 8 ICP patients carrying the c.1954 A > G variant. ICP-b: 6 patients with ICP who carry the c.1954 A > G variant and one other exonic variant. ICP-t:2 patients with ICP who carry the c.1954 A > G variant and two other exonic variants. γ-GT: gamma glutamyl transferase. TBA: total bile acids. ALT: alanine transaminase. AST: aspatate aminotransferase.
From: Association between ABCB4 variants and intrahepatic cholestasis of pregnancy
ICP-b (\(\bar x\)± s) | ICP-t (\(\bar x\)± s) | P | |
|---|---|---|---|
γ-GT (U/L) | 33.3 ± 27.8 | 108 ± 15.6 | 0.013 |
TBA (µmol/L) | 14.4 ± 9.7 | 40.4 ± 22.2 | 0.045 |
ALT (U/L) | 102.8 ± 98.4 | 424.5 ± 242.5 | 0.026 |
AST (U/L) | 88.7 ± 59.9 | 292.0 ± 94.9 | 0.007 |