Table 5 Biochemical findings in 8 ICP patients carrying the c.1954 A > G variant. ICP-b: 6 patients with ICP who carry the c.1954 A > G variant and one other exonic variant. ICP-t:2 patients with ICP who carry the c.1954 A > G variant and two other exonic variants. γ-GT: gamma glutamyl transferase. TBA: total bile acids. ALT: alanine transaminase. AST: aspatate aminotransferase.

From: Association between ABCB4 variants and intrahepatic cholestasis of pregnancy

 

ICP-b (\(\bar x\)± s)

ICP-t (\(\bar x\)± s)

P

γ-GT (U/L)

33.3 ± 27.8

108 ± 15.6

0.013

TBA (µmol/L)

14.4 ± 9.7

40.4 ± 22.2

0.045

ALT (U/L)

102.8 ± 98.4

424.5 ± 242.5

0.026

AST (U/L)

88.7 ± 59.9

292.0 ± 94.9

0.007