Fig. 4 | Scientific Reports

Fig. 4

From: The mediating role of thyroid-related hormones between thyroid dysfunction diseases and osteoporosis: a mediation mendelian randomization study

Fig. 4

The role of OP risk factors and thyroid-related hormones as mediators in the causal link between identified TDFDs and OP. (A) Two-step MR analysis structure. β1 denotes the effect of hyperthyroidism on FT4, β2 denotes the effect of FT4 on OP, β3 denotes the effect of hyperthyroidism on OP. (B) Two-step MR analysis structure. β1 denotes the effect of hypothyroidism on TSH, β2 denotes the effect of TSH on OP, β3 denotes the effect of hypothyroidism on OP.

Back to article page