Table 2 Association between Dietary Live Microbes Intake and MASLD/MetALD/ALD.

From: Effects of dietary live microbes intake on a newly proposed classification system for steatotic liver disease

 

Crude model

Model 1

Model 2

Model 3

 

Model 4

 
 

OR(95%CI)

P value

OR(95%CI)

P value

OR(95%CI)

P value

OR(95%CI)

P value

OR(95%CI)

P value

MASLD

          

Moderate

0.91(0.82, 1.002)

0.055

0.82(0.74, 0.92)

 < 0.001

0.91(0.82, 1.01)

0.09

0.93(0.84, 1.04)

0.22

0.94(0.84, 1.05)

0.28

High

0.74(0.66, 0.83)

 < 0.001

0.74(0.65, 0.84)

 < 0.001

0.80(0.71, 0.91)

 < 0.001

0.81(0.70, 0.93)

0.004

0.84(0.72, 0.97)

0.02

Trend test

 

 < 0.001

 

 < 0.001

 

 < 0.001

 

0.004

 

0.02

MetALD

          

Moderate

0.89(0.73, 1.08)

0.23

0.84(0.68, 1.02)

0.08

0.91(0.73, 1.12)

0.35

0.92(0.74, 1.14)

0.45

0.92(0.74, 1.14)

0.44

High

0.82(0.66, 1.01)

0.06

0.76(0.61, 0.95)

0.02

0.81(0.65, 1.02)

0.07

0.84(0.66, 1.05)

0.13

0.84(0.67, 1.06)

0.15

Trend test

 

0.07

 

0.02

 

0.07

 

0.14

 

0.15

ALD

          

Moderate

0.65(0.53, 0.80)

 < 0.001

0.72(0.58, 0.88)

0.002

0.75(0.57, 0.98)

0.03

0.76(0.58, 1.00)

0.050

0.75(0.57, 0.99)

0.04

High

0.53(0.40, 0.72)

 < 0.001

0.69(0.51, 0.94)

0.02

0.73(0.51, 1.05)

0.09

0.76(0.52, 1.10)

0.15

0.77(0.53, 1.11)

0.16

Trend test

 

 < 0.001

 

0.01

 

0.07

 

0.11

 

0.12

  1. ALD, alcoholic liver disease; CVD, cardiovascular disease; HEI, healthy eating index; MASLD, metabolic dysfunction-associated steatotic liver disease; MetALD, metabolic alcohol-related liver disease; NHANES: National Health and Nutrition Examination Surveys; OR, odds ratio; PIR, poverty income ratio. Crude model was the model without adjustment for covariates. Model 1 was adjusted for age, sex, race, marital status, education level, and PIR. Model 2 was adjusted as for model 1, additionally adjusted for CVD history, physical activity, daily drinking, smoking status, HEI-2015, and NHANES cycles. Model 3 was adjusted as for model 2, additionally adjusted for ALT, AST, GGT, and ALP. Model 4 was adjusted as for model 3, additionally adjusted for HbA1c and TG/HDL-c.