Fig. 1 | Scientific Reports

Fig. 1

From: Single cell analysis identifies distinct CD4 + T cells associated with the pathobiology of pediatric obesity related asthma

Fig. 1

CITE-Seq analysis. (a) UMAP plot of CITE-Seq analysis revealed 22 clusters (0 to 21) within CD4 + T cells from all four study groups. (b) Azimuth-based classification of CD4 + T cells revealed CD4 + T cell subtypes do not completely overlap with the 22 clusters. (c) Stacked bar plot summarizes the proportions of Azimuth-based CD4 + T cell subtypes in each cluster. (d) Cluster-specific expression of Th cell subset-specific transcription factors reveal generalized lack of any cluster for a specific Th cell subset other than cluster 12 for Th1 and cluster 10 for T regulatory cells. (e) Azimuth-based T cell classification overlapped to a large extent with those published by Ding et al.26.

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