Fig. 4

(a) Heatmap of the 20 conserved genes in clusters 0, 3, and 8 that were up- or downregulated in obese asthma (OA) as compared to other three groups (Others). (b) Summary of KEGG (T cell receptor signaling pathway, hemopoetic cell lineage, primary immunodeficiency and Th1 and Th2 differentiation) and GO (RNA polymerase II transcription regulator complex) pathways enriched in these 20 genes.