Fig. 3 | Scientific Reports

Fig. 3

From: Integration of transcriptomics and metabolomics data revealed role of insulin resistant SNW1 gene in the pathophysiology of gestational diabetes

Fig. 3

Biomarker Selection: (A) Identified hub genes were validated using RT-qPCR. Fold change analysis revealed higher expression of SNW1. (B) ROC plot analysis shows higher sensitivity and specificity (96.7%) with higher area under curve (AUC 0.988). Genes highlighted in red colour are upregulated whereas genes highlighted in blue colour are downregulated. (C) MCODE analysis revealed the highest MCODE score (12.75) for SNW1 among all Hub genes. (D) Functional enrichment analysis revealed a possible role in insulin and glucose metabolism.

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