Fig. 8 | Scientific Reports

Fig. 8

From: Integration of transcriptomics and metabolomics data revealed role of insulin resistant SNW1 gene in the pathophysiology of gestational diabetes

Fig. 8

Western blot analysis: Downregulation of SNW1 inhibits the IRS1 while promote GLUT4 expression: Expression of GLUT4 was found to be upregulated while that of IRS1 downregulated when SNW1 was knock-down with SiRNA. Thus, SNW1 is inhibiting the glucose uptake by downregulating the expression of glucose transporter like GLUT4 while up-regulating the expression of IRS1.

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