Table 2 Significant gene ontology (GO) terms and Kyoto Encyclopedia of genes and genomes (KEGG) pathway analyses.

From: Effect of genomic regions harboring putative lethal haplotypes on reproductive performance in closed experimental selection lines of Nellore cattle

Description

P-value

Gene ID

GO:0046546—Development of primary male sexual traits

0.0097

ZFP42, GATA3, LHB, LRP2, BAX, AKR1C3

GO:0008584—Male gonad development

0.0094

ZFP42, GATA3, LHB, LRP, BAX, AKR1C3

GO:0030540—Female genitalia development

0.0027

LRP2, BAX, RBP4

GO:0042445—Hormone metabolic process

0.0157

DHRS9, AKR1C4, CYP26A1, GATA3, CYP26C1, LHB, RBP4, BCO2, AKR1C3

GO:0042593—Glucose homeostasis

0.0185

FGF21, FOXA3, INS, TRPM4, G6PC, RBP4, TRA2B, SMARCB1, TH

GO:0006112—Energy reserve metabolic process

0.0134

GYS1, IGF2, INS, PYGB, PHLDA2

GO:0045995—Regulation of embryonic development

0.0146

RUVBL2, NLRP5, PHLDA2, ACTR8

bta04913—Ovarian steroidogenesis

0.0181

INS, LHB, AKR1C3

bta04114—Oocyte meiosis

0.0307

INS, PPP2R1B, YWHAH, CALM3

bta04911—Insulin secretion

0.0343

INS, TRPM4, CACNA1D