Table 4 Effects of mating classes considering lethal haplotypes carriers on the probabilities of pregnancy loss, stillbirth and pre-weaning mortality in Nellore cattle.

Lethal hap¹	C_Dam × NC_Sire²	NC_Dam × C_Sire³	C_Dam × C_Sire⁴	P-value
Pregnancy loss
10.14	22.41	15.73	39.04	0.04
42.4	49.96	3.9	50.91	0.023
193.7	36.95	47.61	73.66	0.018
935.15	26.87	27.15	210.81	0.02
1419.5	29.75	47.74	58.77	0.013
1739.3	40.69	53.37	275.14	0.003
2214.4	63.92	78.39	84.72	0.048
2291.5	50.35	51.15	72.63	0.002
2293.2	53.33	22.65	182.24	0.024
2922.8	71.02	103.97	161.09	0.002
2923.7	78.36	105.23	162.7	< 0.001
Stillbirth
41.4	61.22	112.4	124.42	< 0.001
42.4	59.06	113.11	141.02	< 0.001
43.4	58.72	95	108.47	< 0.001
44.4	68.93	111.79	129.9	0.004
46.4	71.8	112.5	130.34	< 0.001
193.7	26.51	43.35	187.84	0.008
935.15	50.83	51.83	295.03	< 0.001
1008.1	15.84	12.14	99.12	0.045
1110.12	56.93	52.8	279.03	0.008
1739.3	15.25	16.03	89.79	0.022
2027.5	112.5	181.13	210.24	< 0.001
2214.4	18.27	48.81	54.01	0.043
2620.22	86.51	109.82	144.03	< 0.001
Pre-weaning mortality
10.14	37.55	32.48	54.62	< 0.001
42.4	31.79	28.06	44.03	0.003
44.4	16.77	19.39	77.83	0.03
46.4	23.74	31.38	79.84	0.041
223.1	30.03	26.36	271.72	< 0.001
224.9	40.02	31.79	258.28	< 0.001
225.11	38.73	25.3	268.38	< 0.001
935.15	14.56	21.73	189.56	0.032
1110.12	20.33	14.88	301.4	0.04
2027.5	85.43	72.75	174.88	< 0.001
2214.4	23.1	41.14	101.14	0.015
2620.22	27.14	31.48	139.84	< 0.001
2852.5	23.79	27.3	49.55	0.034
2852.58	36.29	80.19	85	0.008

The effects of the lethal haplotypes are expressed in percentage and represents the odds ratio of the mating class compared to a scenario NC_dam\(\:\times\:\) NC_sire (e.g., in lethal haplotype 10.14 considering pregnancy loss, the result reported in the C_Dam × C_Sire class indicates that this mating class has 39.04% more chance of experiencing pregnancy loss when compared to the mating class NC_Dam × NC_Sire).
¹Lethal haplotypes are discerned by DNA segment number and the corresponding haplotype within segment (e.g., 2620.22 signifies segment 2620 and haplotype 22).
²\(\:{\text{C}}_{\text{D}\text{a}\text{m}}\:\times\:\:{\text{N}\text{C}}_{\text{S}\text{i}\text{r}\text{e}}\): carrier dam with noncarrier sire.
³\(\:{\text{N}\text{C}}_{\text{D}\text{a}\text{m}}\:\times\:\:{\text{C}}_{\text{S}\text{i}\text{r}\text{e}}\): noncarrier dam with carrier sire.
⁴\(\:{\text{C}}_{\text{D}\text{a}\text{m}}\:\times\:\:{\text{C}}_{\text{S}\text{i}\text{r}\text{e}}\): carrier dam with carrier sire.

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