Table 3 Threshold effect analyses of the hs-CRP/HDL-C index on MASLD and advanced hepatic fibrosis using two-piecewise linear regression model.

From: Nonlinear associations of the hs-CRP/HDL-C index with metabolic dysfunction-associated steatotic liver disease and advanced liver fibrosis in US adults: insights from NHANES 2017–2018

Models

MASLD

Advanced hepatic fibrosis

OR (95% CI)

P-value

OR (95% CI)

P-value

Inflection point (K)

0.8

1.2

hs-CRP/HDL-C index < K

19.42 (8.35, 45.14)

< 0.001

4.62 (2.08, 10.27)

< 0.001

hs-CRP/HDL-C index > K

0.11 (0.03, 0.42)

0.001

0.39 (0.05, 3.15)

0.375

Logarithm likelihood ratio test

 

< 0.001

 

0.001

  1. Adjusted for age, gender, race, poverty-to-income ratio, marital status, education level, smoking status, obesity, diabetes mellitus, hypertension, and history of cardiovascular disease, chronic kidney disease, and cancer.
  2. OR odds ratio, CI confidence interval.
  3. P < 0.05 are bolded.
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