Table 4 Distribution and comparison of per admission hospitalisation medical costs (AU$) by post-therapy complications status among cancer patients.

From: Emerging burden of post-cancer therapy complications on unplanned hospitalisation and costs among Australian cancer patients: a retrospective cohort study over 14 years

Variables

Patients experienced no post-therapy complications

Patients experienced at least post-therapy complications

Difference

Mean costs per admission (AU$)

SD

Mean costs per admission (AU$)

SD

Mean difference of costs (95% CI)§

p-value

Type of therapy

 Systemic therapy

2,371

10,744

11,335

34,628

8964 (8881 to 9047)

< 0.001

 Radiation therapy

23,187

59,072

15,776

38,425

-7411 (-13543 to -1279)

0.018

 Systemic therapy and radiotherapy

5,281

16,187

12,279

34,081

6998 (5873 to 8124)

< 0.001

Cancer group

 Oral

na

 

36,577

127,192

na

 

 Bladder

1,840

11,876

11,803

35,197

9963 (9540 to 10386)

< 0.001

 Pancreatic cancer

na

 

72,184

84,047

na

 

 Brain

3,551

14,317

14,022

26,721

10,472 (7862 to 13081)

< 0.001

 Cervical cancer

5,371

24,513

12,701

22,338

7329 (-1549 to 16207)

0.106

 Stomach cancer

4,495

14,740

9,820

23,171

5325 (1739 to 8912)

0.004

 Esophageal cancer

2,194

4,098

8,428

27,124

6234 (5218 to 7250)

< 0.001

 Gastric Cardia

3,060

12,138

8,935

31,675

5875 (5013 to 6737)

< 0.001

 Colorectal cancer

3,774

24,984

7,769

24,905

3995 (938 to 7052)

0.010

 Hodgkin lymphoma

1,442

4,892

5,960

20,930

4518 (4165 to 4871)

< 0.001

 Non-Hodgkin lymphoma

2,868

10,655

14,704

36,372

11,836 (11255 to 12417)

< 0.001

 Multiple myeloma

1,429

8,309

13,885

41,649

12,455 (11777 to 13134)

< 0.001

 Anal canal

2,397

10,523

7,480

24,439

5083 (4488 to 5679)

< 0.001

 Liver

3,180

16,125

6,886

24,792

3705 (2729 to 4681)

< 0.001

 Melanoma of the skin

5,128

16,350

8,248

25,562

3120 (1450 to 4790)

< 0.001

 Pancreas

2,576

14,408

6,783

17,227

4208 (3068 to 5347)

< 0.001

 Lung

3,463

18,130

8,743

26,493

5279 (4599 to 5960)

< 0.001

 Breast

2,093

8,205

7,316

20,358

5223 (4887 to 5558)

< 0.001

 Ovary

1,151

2,224

9,016

25,095

7865 (7175 to 8555)

< 0.001

 Kidney

1,535

4,162

7,940

25,746

6405 (5247 to 7564)

< 0.001

 Thyroid

11,296

17,060

18,470

45,438

7174 (4576 to 9771)

< 0.001

 III-defined sites

na

 

na

 

na

 

 Unspecified malignant neoplasm

2,279

9,135

8,277

26,738

5998 (5662 to 6333)

< 0.001

 Rectal cancer

2,053

7,945

8,234

27,361

6181 (5313 to 7049)

< 0.001

 Bone and bone marrow

4,380

15,523

9,914

33,712

5534 (4657 to 6411)

< 0.001

 Acute lymphoblastic leukemia

1,890

9,895

13,693

39,341

11,803 (11263 to 12343)

< 0.001

 Others

4,593

21,563

10,547

32,186

5954 (4692 to 7216)

< 0.001

Patient’s characteristics

 Patients age group

  18–25 years

1,541

4,164

9,711

33,903

8170 (7260 to 9081)

< 0.001

  26–35 years

2,180

8,548

11,206

29,177

9026 (8391 to 9662)

< 0.001

  36–45 years

2,405

10,533

12,371

37,386

9966 (9534 to 10397)

< 0.001

  46–55 years

2,394

9,964

12,999

40,886

10,605 (10236 to 10974)

< 0.001

  56–65 years

2,251

10,075

10,014

32,933

7763 (7506 to 8020)

< 0.001

  >65 years

3,211

16,168

12,022

33,245

8811 (8487 to 9135)

< 0.001

 Gender

  Male

2,806

12,955

11,729

35,302

8923 (8749 to 9096)

< 0.001

  Female

2,487

12,160

10,976

33,663

8489 (8286 to 8692)

< 0.001

 Indigenous status

  Aboriginal or Torres Strait

2,918

9,201

9,984

29,790

7066 (6578 to 7554)

< 0.001

  Neither Aboriginal nor Torres Strait

2,656

12,828

11,497

34,865

8841 (8698 to 8984)

< 0.001

  Patient refused or unable to ask

955

4,579

13,802

43,631

12,847 (11499 to 14195)

< 0.001

 Year of cancer diagnosis

  2006–2009

3,280

12,971

10,642

34,254

7363 (6981 to 7745)

< 0.001

  2010–2012

2,673

14,867

9,127

27,507

6454 (6144 to 6764)

< 0.001

  2013–2015

2,608

11,015

11,419

34,737

8811 (8518 to 9104)

< 0.001

  2016–2018

2,347

12,473

19,048

49,044

16,701 (16199 to 17204)

< 0.001

  2019–2020

1,733

7,942

27,930

51,807

26,197 (25478 to 26916)

< 0.001

Overall

2,627

12,515

11,418

34,637

8791 (8685 to 8897)

< 0.001

  1. §Bootstrap confidence intervals with 1000 replications using generalised linear regression model, p-value = the probability value. na not available, SD standard deviation, LOS length of stay, CI confidence interval.