Fig. 1

MTT assay of compounds C4 and C5 on HCT116 (A, B), HT29 (C, D) and SW480 (E, F) cell lines for a period of 48 h. Among all the three colorectal cancer cell lines C4 showed the maximum percentage inhibition on HCT116 with Ic50 of 74.71 µg/ml and least inhibition was observed in case of compound C5 on SW480 cells with IC50 of 225.8 µg/ml. The results were determined using nonlinear regression method in GraphPad prism, version 10.1.0 (316).