Table 3 Ashcroft scoring.
From: The role of oxidative stress-related genes in idiopathic pulmonary fibrosis
Fibrosis score | Alveolar septa | Lung structure |
|---|---|---|
0 | No fibrosis | Normal |
1 | Isolated, mild fibrous changes (septal thickness ≤ 3 × normal) | Partially enlarged and loose alveoli; no fibrotic masses |
2 | Obvious fibrous changes (septal thickness > 3 × normal), nodular, but not connected to other septa | Partially enlarged and loose alveoli; no fibrotic masses |
3 | Continuous fibrous alveolar walls (septal thickness > 3 × normal), occupying the majority of the microscopic field | Partially enlarged and loose alveoli; no fibrotic masses |
4 | Distorted | Single fibrotic mass (≤ 10% of microscopic field) |
5 | Distorted | Confluent fibrotic masses (10% < microscopic field ≤ 50%) |
6 | Distorted, mostly absent | Large, continuous fibrotic masses (> 50% of microscopic field); lung architecture mostly absent |
7 | Absent | Alveoli almost completely absent, with fibrotic masses present, but up to 5 airspaces remain |
8 | Absent | Fibrotic mass, complete obliteration |