Fig. 4
Low-input cryopreserved tissues yield similar heterogeneity to single-cell atlases. To evaluate the representativity of single-nuclei data starting with low-input material, we integrated our results with publicly available single-cell atlases. (A–D) Uniform manifold approximation and projection (UMAP) plots of the individual cells identified in each tissue (red) with a corresponding single-cell atlas (grey). Sources for the atlases are available in Table S1. Each dot represents a single nucleus or cell. (E–H) UMAP plots color-coded according to distinct cell types for the brain (9), the bladder (11), the lung (15) and the prostate (10). The cell annotations represent the cell populations found within the reference atlas for the specific tissue. Each dot represents a single nuclei or cell.
