Table 3 Adjusted hazard ratios (95% CI) for risk factors associated with MAKE at 6-, 12- and 24-months post index date. Non-COVID-19 patients were used as the reference group. Adjusted for all demographics, comorbidities and baseline eGFR.

From: Long term outcomes of patients with chronic kidney disease after COVID-19 in an urban population in the Bronx

 

6 Months

P Value

1 Year

P Value

2 Year

P Value

Hospitalized COVID-19

2.94 [2.28,3.79]

 < 0.001

2.24 [1.81,2.76]

 < 0.001

2.03 [1.70,2.42]

 < 0.001

Non-hospitalized COVID-19

1.92 [1.32,2.80]

 < 0.001

1.81 [1.36,2.42]

 < 0.001

1.53 [1.18,1.98]

 < 0.001

Demographics

      

Age

0.99 [0.98,1.00]

0.02

0.99 [0.98,0.99]

 < 0.001

0.99 [0.99,0.99]

 < 0.001

Male sex

1.09 [0.90,1.32]

0.37

1.15 [1.00,1.32]

0.06

1.14 [1.03,1.27]

0.01

Ethnicity

1.09 [0.85,1.40]

0.49

1.20 [0.99,1.44]

0.06

1.17 [1.02,1.35]

0.02

Black Race

1.18 [0.93,1.49]

0.17

1.19 [0.99,1.41]

0.06

1.09 [0.96,1.24]

0.18

Comorbidities

      

Hypertension

2.25 [1.31,3.86]

0.003

1.58 [1.13,2.21]

0.01

1.28 [1.02,1.59]

0.03

Diabetes

1.19 [0.98,1.45]

0.08

1.29 [1.12,1.50]

 < 0.001

1.34 [1.21,1.50]

 < 0.001

COPD

1.15 [0.89,1.49]

0.29

1.13 [0.93,1.37]

0.23

1.16 [1.00,1.35]

0.05

Asthma

1.01 [0.80,1.27]

0.95

1.00 [0.84,1.20]

0.99

1.03 [0.90,1.18]

0.65

Liver

1.46 [1.19,1.80]

 < 0.001

1.32 [1.13,1.55]

 < 0.001

1.24 [1.10,1.40]

 < 0.001

Smoking

1.54 [1.26,1.89]

 < 0.001

1.42 [1.22,1.66]

 < 0.001

1.24 [1.10,1.39]

 < 0.001

Heart Failure

1.33 [1.08,1.65]

0.01

1.46 [1.25,1.71]

 < 0.001

1.39 [1.23,1.57]

 < 0.001

Cancer

1.30 [1.05,1.61]

0.02

1.21 [1.02,1.42]

0.03

1.28 [1.13,1.44]

 < 0.001

Obesity

0.89 [0.73,1.09]

0.25

0.89 [0.76,1.03]

0.11

0.97 [0.87,1.09]

0.64

Baseline eGFR

0.98 [0.97,0.98]

 < 0.001

0.97 [0.96,0.98]

 < 0.001

0.97 [0.96,0.97]

 < 0.001

AKI

5.42 [4.02,7.31]

 < 0.001

4.02 [3.07,5.25]

 < 0.001

3.05 [2.39,3.89]

 < 0.001

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