Fig. 2
From: Identification of shared genetic loci for asthma, allergic rhinitis, and pollinosis in East Asians
Regional plots for novel pleiotropic loci at 9q32 and 10q25.2. This figure shows regional plots (LocusZoom plots) for two newly identified genetic loci at 9q32 and 10q25.2, which are associated with multiple conditions and are specific to East Asian populations. Panel A shows the genetic associations at the 9q32 locus. The most significant genetic variant, rs57656777, is marked with a purple diamond. The y-axis indicates the strength of the genetic associations (measured by the -log10 of the p-value, which is a statistical measure of significance), while the x-axis shows the location of this variant along chromosome 9 (in megabases, Mb). The blue line represents the recombination rate, which shows how often nearby genetic variants are inherited together. Panel B shows the genetic associations at the 10q25.2 locus. The top variant here, rs139174066, is also marked with a purple diamond. As in Panel A, the y-axis represents the strength of the associations, and the x-axis shows the position on chromosome 10. The blue line again indicates the recombination rate in this region. The circles represent other genetic variants in this area, with the color of the circles showing how strongly each variant is linked to the main variant (lead SNP) – stronger links are indicated by darker colors.
