Table 2 Associations of MTAG between allergic rhinitis and asthma in East Asians.
From: Identification of shared genetic loci for asthma, allergic rhinitis, and pollinosis in East Asians
Trait | SNP | CHR | BP | A1 | A2 | Allergic rhinitis | Asthma | MTAG | Genes | Annotation | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta | P-value | Beta | P-value | beta | P-value | ||||||||
Allergic rhinitis (Trait1) | rs59789950 | 2 | 203,760,647 | C | T | −0.090 | 1.99E-07 | −0.086 | 3.88E-10 | −0.022 | 5.66E-12 | CD28 | New |
rs9880787 | 3 | 188,420,544 | A | G | 0.083 | 1.87E-06 | 0.060 | 1.35E-05 | 0.019 | 6.51E-09 | LPP | New | |
rs28529717 | 6 | 32,647,186 | G | A | −0.072 | 3.60E-04 | −0.152 | 1.11E-21 | −0.023 | 2.56E-11 | MHC region | New | |
rs11256019 | 10 | 9,002,711 | A | G | −0.057 | 9.33E-04 | −0.126 | 1.14E-20 | −0.021 | 2.11E-10 | GATA3 | New | |
rs139174066 | 10 | 112,318,977 | A | G | 0.148 | 4.34E-06 | 0.101 | 8.96E-05 | 0.031 | 4.00E-08 | GPAM | New* | |
rs3024590 | 16 | 27,349,307 | C | T | 0.072 | 1.34E-04 | 0.123 | 3.41E-16 | 0.023 | 1.86E-10 | IL4R | New | |
Asthma (Trait1) | rs12999364 | 2 | 102,357,669 | T | C | 0.058 | 8.31E-04 | 0.082 | 2.41E-09 | 0.021 | 1.24E-09 | IL1RL1 | Known |
rs3769684 | 2 | 203,720,036 | C | T | −0.080 | 3.22E-06 | −0.090 | 2.71E-11 | −0.023 | 1.11E-11 | CD28 | Known | |
rs78218185 | 6 | 32,464,723 | A | G | 0.106 | 2.12E-05 | 0.279 | 4.12E-43 | 0.067 | 1.97E-44 | MHC region | Known | |
rs7081353 | 10 | 9,002,372 | G | A | −0.056 | 9.98E-04 | −0.126 | 1.12E-20 | −0.032 | 2.67E-21 | GATA3 | Known | |
rs10995250 | 10 | 62,637,161 | A | G | −0.061 | 3.46E-04 | −0.074 | 4.19E-08 | −0.019 | 2.32E-08 | ADO | Known | |
rs3024577 | 16 | 27,346,882 | G | A | 0.072 | 1.36E-04 | 0.123 | 3.15E-16 | 0.031 | 9.68E-17 | IL4R | Known | |
