Fig. 1

The bar plot illustrates the number of differentially expressed genes across the specified contrasts. Total number of genes upregulated in each contrast are represented in red, while downregulated genes are shown in blue. Contrasts include: LPS versus Brachy, LPS versus pBD + Brachy, Brachy versus pBD + Brachy, LPS versus pBD, Brachy versus pBD, pBD + Brachy versus pBD, LPS versus Control, Brachy versus Control, pBD + Brachy versus Control, and pBD versus Control. A dotted-line box highlights the contrast “Brachy versus Control,” and a solid-line box emphasizes “Brachy versus pBD + Brachy,” as these contrasts are central to the discussion in this manuscript.