Fig. 3 | Scientific Reports

Fig. 3

From: Porcine β-defensin 5 (pBD-5) modulates the inflammatory and metabolic host intestinal response to infection

Fig. 3

Significantly affected pathways when contrasting pBD versus Control groups. Pre-ranked GSEA approach with a pathway significance cut-off FDR = 0.1. The Kyoto Encyclopedia of Genes and Genomes (KEGG) database of genes was used. (a) Two pathways (nodes) are connected if they share 10% or more genes. Red and green represents up- and down-regulated pathways, respectively. Darker nodes are more significantly enriched gene sets. Bigger nodes represent larger gene sets. Thicker edges represent more overlapped genes. (b, c) Top differentially expressed genes in the most significantly enriched upregulated (red) or downregulated (green) pathways.

Back to article page