Fig. 1

Time-kill curves of two cephamycin-susceptible ESBL-producing E. coli exposed to cefoxitin, cefmetazole, and flomoxef. (A) ECO-2, inoculum 5 × 105 CFU/mL; (B) ECO-2, inoculum 5 × 107 CFU/mL; (C) ECO-8, inoculum 5 × 105 CFU/mL; (B) ECO-8, inoculum 5 × 107 CFU/mL. The lower limit of detection for this assay was 10 CFU/mL.