Fig. 2

Debatching of the dataset. (A, B) Boxplots plot of GEO Datasets (Combined Datasets) before to (A) and after (B) normalization. (C, D) PCA plots of GEO datasets (Combined Datasets) before (C) and after (D) batch effect elimination. PCA: Principal Component Analysis. Blue represents the GSE31821 dataset, red represents the GSE41177 dataset, and purple indicates the GSE79768 dataset.