Fig. 3

Effects of EVO on main organs, especially the spleen, in melanoma-bearing mice. (A) Main organs of melanoma-bearing mice were collected and subjected to H&E staining, compared with wild-type mice of the control group (scale bar = 50 μm) (n = 4). (B–D) The spleen from three groups of mice was collected (C), stained with H&E (scale bar: upper = 100 μm, lower = 50 μm) (B), and weighed (D) (n = 4). Data are expressed as mean ± SD. *** p < 0.001.