Fig. 4 | Scientific Reports

Fig. 4

From: Evodiamine inhibits programmed cell death ligand 1 expression via the PI3K/AKT signaling pathway to regulate antitumor immunity in melanoma

Fig. 4

Regulation of T-cells in melanoma-bearing mice by EVO. (A,B) Percentages of CD4+ T cells and CD8+ T cells in (A) bone marrow and (B) spleen were detected by flow cytometry (n = 2). (C,D) Tumor and spleen sections were analyzed by IHC for CD4 and CD8, with quantitative analysis (scale bar = 50 μm) (n = 4). Data are expressed as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001.

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