Table 5 Subgroup analyses for the association between MDS and risk of stroke.

From: Association of magnesium depletion score with increased stroke incidence and mortality risks in a comprehensive analysis

Characteristics

MDS, OR (95% CI)

p for trend

p for interaction

None to low

Middle

High

Age (years)

0.006

 <60

Ref

1.47 (1.19, 1.83)

1.58 (1.22, 2.06)

< 0.001

 

 ≥60

Ref

1.85 (1.27, 2.71)

2.76 (1.57, 4.84)

< 0.001

 

Sex

0.045

 Male

Ref

2.05 (1.57, 2.69)

2.14 (1.51, 3.01)

< 0.001

 

 Female

Ref

1.51 (1.15, 1.99)

1.64 (1.17, 2.30)

0.004

 

LE8 score

0.004

 Low (0–50)

ref

2.25 (0.81, 6.20)

2.37 (1.14, 4.91)

0.033

 

 Median (50–80)

ref

1.62 (1.31, 2.00)

2.23 (1.75, 2.84)

< 0.001

 

 High (80–100)

Ref

1.79 (1.32, 2.43)

1.96 (1.39, 2.76)

< 0.001

 

Health behaviors score

0.005

 Low (0–50)

Ref

1.77 (1.16, 2.72)

2.65 (1.62, 4.34)

< 0.001

 

 Median (50–80)

Ref

1.84 (1.43, 2.37)

2.48 (1.88, 3.28)

< 0.001

 

 High (80–100)

Ref

1.61 (1.22, 2.13)

1.74 (1.25, 2.43)

< 0.001

 

Health factors score

0.011

 Low (0–50)

Ref

1.90 (1.17, 3.10)

2.52 (1.32, 4.80)

0.001

 

 Median (50–80)

Ref

1.80 (1.43, 2.27)

2.35 (1.80, 3.07)

< 0.001

 

 High (80–100)

Ref

1.68 (1.25, 2.25)

2.18 (1.59, 2.99)

< 0.001

 
  1. Each stratification was adjusted for age, sex, race, education, PIR, smoking, drinking, hypertension, diabetes, hyperlipidemia, creatinine, blood urea nitrogen, serum uric acid, calcium intake, magnesium intake, LE8 score, and eGFR except the stratification factor itself.
  2. OR odds ratio, CI confidence interval, ref reference.
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