Table 3 Patients’ general information.

From: Role of PLA2R domain antibodies and epitope spreading in risk stratification and prediction of proteinuria remission in primary membranous nephropathy

 

Low-to-medium risk group

(n = 12)

High-to-extremely-high risk group

(n = 89)

P

Gender

7:5

58:31

0.643

Age

46.08 ± 14.21

52.55 ± 12.54

0.102

Hypertension

3/12

57/89

0.010

Diabetes

1/12

18/89

0.322

Proteinuria

3.41 ± 1.81

5.61 ± 1.90

0.000

Serum albumin

30.20 ± 4.27

20.89 ± 3.86

0.000

Serum creatinine

79.05 ± 19.75

88.06 ± 59.13

0.603

EGFR

94.95 ± 14.77

88.52 ± 25.76

0.401

PLA2R-IgG(TRFIA)

65.15 ± 96.37

158.83 ± 199.37

0.113

PLA2R-IgG4(TRFIA)

2295.52 ± 3774.05

6503.96 ± 6940.21

0.043

PLA2R-CySR-IgG(TRFIA)

30.39 ± 38.83

87.74 ± 150.49

0.194

PLA2R-CySR-IgG4(TRFIA)

725.45 ± 1380.93

2194.48 ± 6495.32

0.068

PLA2R-CTLD1-IgG(TRFIA)

16.17 ± 23.60

43.09 ± 84.39

0.276

PLA2R-CTLD1-IgG4(TRFIA)

305.11 ± 852.08

478.83 ± 1181.35

0.628

PLA2R-CTLD678-IgG(TRFIA)

18.54 ± 25.69

118.93 ± 376.76

0.360

PLA2R-CTLD678-IgG4(TRFIA)

273.12 ± 597.78

2548.87 ± 6198.85

0.001

IgG Epitope spreading

5/12

65/89

0.027

IgG4 Epitope spreading

6/12

74/89

0.008