Fig. 1 | Scientific Reports

Fig. 1

From: Urinary prostaglandin D2 and E2 metabolites are elevated with disease severity in patients with Fukuyama congenital muscular dystrophy

Fig. 1

Biosynthesis and metabolism of PGD2 and PGE2 to tetranor-PGDM and tetranor-PGEM. Enzymes and their inhibitors and major substances in the PG cascade are shown, in which the inhibitors are circled and enzymes are indicated in bold letters. NSAIDs, non-steroid anti-inflammatory drugs; TXA2, thromboxane A2; LPGDS, lipocalin-type PGD2 synthase; PGES, PGE2 synthase.

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