Fig. 11
Analysis of PCD Signature in single-cell RNA sequencing data. (a) AUC histogram plot showing the distribution of area under the curve (AUC) scores for the PCD signature across the dataset. The vertical line marks the threshold for significant AUC values (AUC > 0.15). (b) t-SNE plot illustrating the expression levels of the PCD signature across different cell types in the dataset. Cells are colored based on their AUC scores, with higher scores indicating stronger expression of the PCD signature. (c) Violin plots showing the distribution of PCD scores across various cell types. (d) Bubble plot showing the KEGG pathway enrichment analysis37,38,39 of genes associated with the PCD signature. (e) GSEA plot depicting the enrichment of various hallmark pathways related to the PCD signature.
