Table 2 Material properties used in process modeling.
From: Randomized-field microwave-assisted pharmaceutical lyophilization with closed-loop control
Property | Units | Value |
|---|---|---|
Dielectric loss coefficient of ice, \(\epsilon^{\prime \prime}_\text {f}\) | None | \(8. \times 10^{-4}\) |
Dielectric loss coefficient of glass, \(\epsilon^{\prime \prime}_\text {vw}\) | None | \(2.4 \times 10^{-2}\) |
Solution (water) density, \(\rho _\text {solution}\) | g/ml | 1.0 |
Ice density, \(\rho _\text {ice}\) | g/ml | 0.918 |
Ice heat capacity, \(C_\text {p,f}\) | J/kg/K | 2,050 |
Glass heat capacity, \(C_\text {p,vial}\) | J/kg/K | 840 |
Mass of 6R glass vial, \(m_\text {vial}\) | g | 7.6 |
Heat of sublimation of ice, \(\Delta H_\text {sub}\) | cal/g | 678. |
Vapor pressure over ice, \(p_\text {sub}\) | mTorr | \(2.698\times 10^{10} \cdot \exp \left( \frac{-6144.96 \text K}{T_\text {sub}} \right)\) |
