Table 6 Solid-state NMR \(^1H\) \(T_1\) and \(^1H\) \(T_{1\rho }\) relaxation times for attenuated live virus formulations.
From: Randomized-field microwave-assisted pharmaceutical lyophilization with closed-loop control
Cycle | \(^{{{1}}}\)H \({\text {T}}_{{ {1}}}\) relaxation time (s) | \(^{{ {1}}}\)H \({\text {T}}_{1\rho }\) relaxation time (ms) | ||
|---|---|---|---|---|
169–177 ppm | 69–74 ppm | 169–177 ppm | 69–74 ppm | |
Conventional | 4.62 ± 0.06 | 5.49 ± 0.12 | 7.96 ± 0.20 | 8.05 ± 0.17 |
RF | 4.31 ± 0.12 | 5.14 ± 0.12 | 8.88 ± 0.19 | 8.50 ± 0.17 |
