Table 5 Effectiveness of inhaled antibiotics at low doses.

From: Tolerance and effectiveness of inhaled antibiotics at standard or low doses in COPD patients with chronic Pseudomonas aeruginosa bronchial infection

 

Inhaled antibiotics at low doses

(groups 2, 5)

n = 19

 

Previous year

Posterior year

Change 1 (p2)

Symptoms

   

Daily expectoration, (%)

73.7

36.8

36.8 (0.023)

Type expectoration

   

White, (%)

26.3

76.5

−50.2 (0.013)

Mucopurulent, (%)

52.6

17.6

35.0 (0.228)

Purulent, (%)

21.1

5.9

15.2 (0.371)

Dyspnoea (mMRC))

2.5 (1.0)

2.0 (1.1)

0.5 (0.008)

Exacerbations in previous year

   

Ambulatory

3.7 (1.6)

1.6 (1.5)

2.1 (0.003)

Hospital admissions

1.5 (1.9)

0.9 (1.3)

0.6 (0.079)

Days of hospitalization

26.8 (16.0)

19.4 (17.8)

7.4 (0.036)

Microbiological data

   

Number of PA isolation

2.9 (1.1)

0.9 (1.2)

2.0 (0.001)

Respiratory function

   

FVC postBD %

69.7 (13.3)

64.4 (13.8)

5.3 (0.016)

FEV1 postBD %

48.1 (16.4)

43.6 (13.5)

4.5 (0.641)

Oxygen saturation %

95.2 (2.2)

94.7 (1.8)

0.6 (0.254)

  1. Footnote: *Data presented as mean (SD) unless otherwise specified. mMRC: modified Medical Research Council dyspnea scale; FVC: forced vital capacity; FEV1: Forced expiratory volume in 1 s; PA: Pseudomonas aeruginosa.
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