Fig. 2

Forest plot of overall survival in subgroups and overall population of patients with newly diagnosed brain metastases from non-small cell lung cancer receiving first-line immunotherapy. This forest plot reflects the comparison of the efficacy between ICI + BRT and ICI in each subgroup. An HR less than 1 indicates the superiority of ICI + BRT, while an HR greater than 1 indicates the superiority of ICI. Only in the subgroup of patients who received Hormones or mannitol, ICI + BRT was significantly superior to ICI.