Fig. 3 | Scientific Reports

Fig. 3

From: Establishing metrics of clinically meaningful change for treating knee osteoarthritis with a combination of autologous orthobiologics

Fig. 3

Change in outcomes (ΔPROMs) after receiving autologous BMC and PRP treatment for knee OA. Patient reported changes in IKDC (a), LEFS (b), NPS (c), and SANE (d) scores at the 12-month follow-up (n = 295). Dashed lines indicate no change. Solid lines and overhead values represent mean ± standard deviation. The standard deviation of a ΔPROM (bold) multiplied by one-half represents a common approach for deriving a distribution-based MCID.

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