Table 5 Determination of TAM and TTD in spiked human plasma and spiked human urine the proposed chromatographic method.

From: Green HPLC-Fluorescence detection method for concurrent analysis of Tamsulosin hydrochloride and Tolterodine tartrate in dosage forms and biological fluids

Conc. Level

% Recovery ± RSD a

µg mL−1

Spiked plasma

Spiked urine

Intra-day precision

Inter-day precision

Intra-day precision

Inter-day precision

TAM

    

0.20

99.31 ± 0.96

99.46 ± 1.53

98.71 ± 1.03

99.38 ± 1.44

0.80

99.36 ± 1.14

100.64 ± 1.39

101.35 ± 0.92

101.55 ± 1.06

1.25

100.81 ± 1.20

100.97 ± 1.29

99.90 ± 0.58

99.59 ± 1.03

TTD

    

2.00

101.41 ± 0.78

101.65 ± 1.20

99.93 ± 0.34

99.53 ± 1.31

8.00

101.29 ± 1.02

100.56 ± 1.27

101.08 ± 0.86

101.84 ± 1.04

12.50

101.39 ± 1.53

101.79 ± 1.41

100.44 ± 0.63

101.08 ± 0.89

  1. a Mean of three determinations.
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