Table 1 Baseline clinical and laboratory characteristics of patients with SA-noAKI and SA-AKI.

From: Biomarkers of cell cycle arrest, microcirculation dysfunction, and inflammation in the prediction of SA-AKI

Variable

SA-noAKI

n = 46

SA-AKI

n = 50

P

Clinical parameters

Age, y

78 (63.75, 84)

73.5 (61.25, 83.75)

0.479

Male, n (%)

27 (58.7%)

29 (58%)

0.945

APACHE

14.5 (10.25, 19)

17 (13, 21)

0.079

SOFA

5 (2, 8)

10 (6.25, 10.75)

< 0.001**

Hypertension, n (%)

20 (43.48%)

29 (58%)

0.155

Diabetes mellitus, n (%)

15 (32.61%)

21 (42%)

0.342

Nephrotoxic drugs, n (%)

39 (84.78%)

43 (86%)

0.866

Vasopressor, n (%)

23 (50%)

37 (74%)

0.015*

Diuretics, n (%)

11 (23.91%)

21 (42%)

0.060

Tumors, n (%)

7 (15%)

9 (18%)

0.715

Infection site

Lung, n (%)

34 (73.9%)

22 (44%)

 

Urinary system, n (%)

6 (13%)

3 (6%)

 

Abdominal, n (%)

5 (10.9%)

18 (36%)

 

Soft tissue, n (%)

0 (0%)

5 (10%)

 

Central nervous system, n (%)

1 (2%)

1 (2%)

 

Endocarditis, n (%)

0 (0%)

1 (2%)

 

Septic shock, n (%)

12 (26.09%)

30 (60%)

0.001**

Hospital death, n (%)

11 (23.91%)

17 (34%)

0.277

Laboratory parameters

Scr at admission, µmol/L

71.5 (62.25, 88)

83.5 (71, 88.75)

0.164

WBC, ×109/L

12.17 (8.35, 15.6)

13.23 (9.01, 19.6)

0.294

Neut, ×109/L

10 (6.14, 13.8)

12.26 (7.15, 18.05)

0.129

NLR

10.39 (4.99, 26.92)

18.68 (11.48, 25.94)

0.021*

PLT, ×109/L

214.5 (139.75, 268.25)

179 (120.25, 263.75)

0.218

CRP, mg/L

31.56 (9.78, 66.53)

45.74 (31.29, 92.69)

0.023*

PCT, ng/mL

0.57 (0.11, 8.29)

14.51 (1.29, 48.15)

< 0.001**

BUN, mmol/L

8.15 (5.53, 14.6)

17.05 (9.7, 21.08)

< 0.001**

SUA, µmol/L

323 (234.75, 418)

474.5 (358.75, 568.5)

< 0.001**

Fib, g/L

3.95 (2.77, 4.62)

4.22 (3.46, 6.6)

0.117

D-D, µg/mL

0.91 (0.44, 2.27)

1.36 (0.89, 3.49)

0.004**

FDP, mg/L

7.5 (4.2, 15.1)

11.65 (7, 24.58)

0.002**

  1. APACHE  acute physiology and chronic health evaluation, SOFA  sequential organ failure assessment, Scr  serum creatinine, WBC white blood cell count, Neut  neutrophils count, NLR neutrophil-to-lymphocyte ratio, PLT platelet, CRP C-reactive protein, PCT procalcitonin, BUN urea, SUA  serum uric acid, Fib  fibrinogen, D-D  D-dimer,FDP fibrin degradation products. *P < 0.05, **P < 0.01.