Table 1 Baseline characteristics of the groups stratified based on PS.
Performance status | P for trend | |||
|---|---|---|---|---|
Grade 0 (N = 33,934) | Grade 1 (N = 21,460) | Grade 2–4 (N = 12,960) | ||
Age (years) | 62.2 ± 12.0 | 66.9 ± 11.3 | 73.2 ± 10.7 | < 0.001 |
Men (%) | 66.3 | 58.0 | 53.0 | < 0.001 |
Dialysis vintage (month) | 81 (42–144) | 78 (40–144) | 68 (36–123) | < 0.001 |
Dialysis time (hour/week) | 12.2 ± 1.4 | 12.1 ± 1.4 | 11.6 ± 1.4 | < 0.001 |
Hemodiafiltration (%) | 7.7 | 7.4 | 6.3 | < 0.001 |
BMI (kg/m2) | 21.7 ± 3.8 | 21.4 ± 3.9 | 20.6 ± 4.7 | < 0.001 |
Kt/V | 1.44 ± 0.29 | 1.46 ± 0.29 | 1.44 ± 0.29 | 0.058 |
nPCR (g/kg/day) | 0.91 ± 0.17 | 0.89 ± 0.17 | 0.84 ± 0.17 | < 0.001 |
Cause of kidney failure (%) | ||||
Glomerulonephritis | 46.0 | 39.9 | 29.7 | < 0.001 |
Diabetes | 27.9 | 34.2 | 45.1 | < 0.001 |
Hypertension | 5.5 | 7.0 | 9.0 | < 0.001 |
Polycystic kidney disease | 4.5 | 3.7 | 2.1 | < 0.001 |
Others | 7.1 | 7.0 | 7.7 | 0.105 |
Unknown | 8.9 | 8.3 | 6.4 | < 0.001 |
Past history (%) | ||||
Myocardial infarction | 6.9 | 9.7 | 12.2 | < 0.001 |
Cerebral hemorrhage | 3.4 | 4.8 | 11.7 | < 0.001 |
Cerebral infarction | 9.7 | 15.3 | 32.4 | < 0.001 |
Amputation | 1.5 | 2.6 | 8.0 | < 0.001 |
Fracture | 0.9 | 2.0 | 7.3 | < 0.001 |
PTx | 7.4 | 7.6 | 4.2 | < 0.001 |
PEIT | 1.6 | 1.6 | 0.9 | < 0.001 |
Laboratory test | ||||
Corrected calcium (mg/dL) | 9.3 ± 0.8 | 9.3 ± 0.8 | 9.4 ± 1.0 | 0.003 |
Phosphate (mg/dL) | 5.4 ± 1.4 | 5.2 ± 1.4 | 4.8 ± 1.4 | < 0.001 |
Intact PTH (pg/mL) | 131 (70–214) | 126 (66–207) | 112 (56–190) | < 0.001 |
Albumin (g/dL) | 3.8 ± 0.3 | 3.7 ± 0.3 | 3.5 ± 0.4 | < 0.001 |
Creatinine (mg/dL) | 11.7 ± 2.7 | 10.7 ± 2.5 | 9.0 ± 2.4 | < 0.001 |
CRP (mg/dL) | 0.1 (0.0–0.2) | 0.1 (0.0–0.3) | 0.1 (0.0–0.5) | < 0.001 |
Hemoglobin (g/dl) | 10.8 ± 1.1 | 10.7 ± 1.2 | 10.5 ± 1.3 | < 0.001 |
Magnesium (mg/dL) | 2.7 ± 0.5 | 2.6 ± 0.5 | 2.5 ± 0.5 | < 0.001 |
ALP (IU/L) | 244 ± 122 | 261 ± 127 | 287 ± 151 | < 0.001 |
Medication (%) | ||||
Calcium carbonate | 68.0 | 65.9 | 53.3 | < 0.001 |
Sevelamer | 38.9 | 33.4 | 19.5 | < 0.001 |
Lanthanum carbonate | 17.6 | 15.4 | 9.0 | < 0.001 |
Other phosphate binders | 4.6 | 3.7 | 2.2 | < 0.001 |
Oral VDRA | 39.3 | 40.6 | 36.2 | < 0.001 |
Intravenous VDRA | 32.7 | 30.9 | 23.7 | < 0.001 |
Cinacalcet | 17.0 | 14.4 | 8.5 | < 0.001 |
Dialysate calcium (%) | ||||
<2.75 mEq/L | 36.8 | 38.4 | 38.7 | < 0.001 |
2.75-<3.0 mEq/L | 9.0 | 8.2 | 8.4 | 0.003 |
3.0- mEq/L | 50.2 | 49.3 | 49.2 | 0.019 |
Acetate-free dialysis | 3.9 | 4.1 | 3.8 | 0.727 |
Performance status (%) | ||||
Grade 0 | 100.0 | 0.0 | 0.0 | |
Grade 1 | 0.0 | 100.0 | 0.0 | |
Grade 2 | 0.0 | 0.0 | 60.2 | |
Grade 3 | 0.0 | 0.0 | 26.3 | |
Grade 4 | 0.0 | 0.0 | 13.5 | |
