Fig. 2

The mRNA expression of ABCE1 among various cancers. (A-C) Expression levels of ABCE1 in different cancer types from TCGA datasets from UALCAN, TIMER and GEPIA databases. The graphs were represented in box plot, x-axis denotes the different types of cancer, and y-axis denotes the expression level (log₂ [TPM]). The cancer expression levels were compared between normal (blue color) and tumour cancer samples (red color). (D) GEPIA datasets represents the pan-cancer view and highlighted particularly COAD datasets of ABCE1 expression. (E) GDC datasets represents the heatmap using TCGA datasets by clinical characteristics (Race, age at diagnosis, vital status, and Days to death) and data types (clinical, biospecimen, sequencing reads, SNV, CNV, and transcriptome profiling) of COAD samples. It denotes the mutation frequency and list of genes (y-axis) associated with ABCE1 in COAD datasets. (F) The heat map illustration denotes the expression levels of ABCE1 in TCGA-COAD datasets. The expression levels were denoted from low (normal) to high (high) by blue to red color. ABCE1 expression results among various cancers were displayed as histogram and color images are available online. Statistical significance: *p < 0.05, **p < 0.001, and ***p < 0.0001. TCGA, The Cancer Genome Atlas; TIMER, Tumour Immune Estimation Resource; TPM, Transcript Per Million; GDC, Genomic Data Commons; COAD, Colon Adenocarcinoma; SNV, Single Nucleotide Variant; CNV, Copy Number Variant.