Fig. 7 | Scientific Reports

Fig. 7

From: Innovative peptide therapeutics targeting IL17RA to regulate inflammatory responses

Fig. 7

Evaluation of IL17RA mAb or AL-8(0)-Mediated Inhibition of the NF-κB Pathway in IL-17RA-Expressing Cells After 24 h of IL-17 A Stimulation. (A-D) Expression Levels of Phosphorylated NF-κB p65 Protein (p-NFκB p65) in THP-1(A), RAW264.7(B), HaCaT(C), and NIH3T3(D). (E-H) Expression Levels of Phosphorylated IκBα p65 Protein (p-IκBα) in THP-1(E), RAW264.7(F), HaCaT(G), and NIH3T3(H). The data are presented as the mean ± SEM. p-values for the indicated compounds are **p < 0.01 (ANOVA).

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