Table 1 30 Most abundant antimicrobial resistance genes (ARGs) with their class, functions and abundance.

From: Abundance and transmission of antibiotic resistance and virulence genes through mobile genetic elements in integrated chicken and fish farming system

Genes

Description

Mechanism

Droppings

Sediment

pvdL

Peptide synthase PvdL Pyoverdine

Nutritional/Metabolic factor

0%

100%

pvdI

Peptide synthase Pyoverdine

Nutritional/Metabolic factor

0%

100%

chpA

Signal transduction system Type IV pili

Adherence

0%

100%

pchF

Pyochelin synthetase PchF Pyochelin

Nutritional/Metabolic factor

0%

100%

clpV1

Type VI secretion system AAA + family ATPase HSI-1

Effector delivery system

32.38%

67.62%

ppkA

Serine/threonine protein kinase PpkA HSI-1

Effector delivery system

28.11%

71.89%

tssH-5/clpV

Clp-type ATPase chaperone protein T6SS-1

Effector delivery system

0%

100%

tssH

Type VI secretion system ATPase TssH HSI-2

Effector delivery system

35.72%

64.28%

pchE

Dihydroaeruginoic acid synthetase PchE Pyochelin

Nutritional/Metabolic factor

0%

100%

algC

Phosphomannomutase AlgC Alginate

Biofilm

34.03%

65.97%

pvdD

Pyoverdine synthetase D Pyoverdine

Nutritional/Metabolic factor

0%

100%

icmF1/tssM1

Type VI secretion system protein IcmF1 HSI-1

Effector delivery system

0%

100%

phzE1

Phenazine biosynthesis protein PhzE Pyocyanin

Nutritional/Metabolic factor

27.99%

72.01%

pilJ

Twitching motility protein PilJ Type IV pili

Adherence

37.59%

62.41%

flhA

Flagellar biosynthesis protein FlhA Flagella

Motility

38.95%

61.05%

pvdJ

Pyoverdine biosynthesis protein PvdJ Pyoverdine

Nutritional/Metabolic factor

0%

100%

tse5/rhsP1

Toxin protein Tse5 HSI-1 T6SS secreted effectors

Effector delivery system

0%

100%

xcpR

General secretion pathway protein E Xcp secretion system

Effector delivery system

32.44%

67.56%

PA1458

Two-component sensor Flagella

Motility

33.4%

66.6%

cheA

Chemotaxis two-component sensor kinase CheA Flagella

Motility

0%

100%

tsr

Methyl-accepting chemotaxis protein I Flagella

Motility

0%

100%

pilT

Twitching motility protein PilT Type IV pili

Adherence

41.06%

58.94%

fleQ

Transcriptional regulator FleQ Flagella

Motility

32.82%

67.18%

tssM

Type VI secretion system membrane subunit TssM HSI-

2

Effector delivery system

0%

100%

fimX

Protein FimX Type IV pili

Adherence

30.31%

69.69%

  1. *Top 25 Virulence factors only appeared in Droppings and Sediment.