Table 2 Association between social isolation score and mortality in individuals with arthritis.

From: Social isolation and risk of mortality in middle-aged and older adults with arthritis: a prospective cohort study of four cohorts

 

Event/N (%)

Model 1

Model 2

 

HR (95% CI)

P-value

HR (95% CI)

P-value

NHATS

 Per unit increased

1011/3872 (26.11)

1.42 (1.33, 1.52)

< 0.0001

1.22 (1.14, 1.30)

< 0.0001

 Score = 0

68/443 (15.35)

1 (ref)

1 (ref)

1 (ref)

1 (ref)

 Score = 1

237/1129 (20.99)

1.50 (1.14, 1.96)

0.0033

1.28 (0.98, 1.69)

0.0725

 Score = 2

330/1236 (26.70)

2.01 (1.55, 2.61)

< 0.0001

1.54 (1.18, 2.01)

0.0015

 Score ≥ 3

376/1064 (35.34)

2.96 (2.28, 3.83)

< 0.0001

1.87 (1.43, 2.44)

< 0.0001

ELSA

 Per unit increased

382/3259 (10.86)

1.25 (1.11, 1.41)

0.0002

1.10 (0.97, 1.25)

0.1237

 Score = 0

100/1132 (8.83)

1 (ref)

1 (ref)

1 (ref)

1 (ref)

 Score = 1

193/1455 (13.26)

1.57 (1.23, 2.00)

0.0002

1.32 (1.02, 1.71)

0.0328

 Score = 2

70/553 (12.66)

1.58 (1.16, 2.14)

0.0035

1.26 (0.91, 1.73)

0.1609

 Score ≥ 3

19/119 (15.97)

2.00 (1.22, 3.27)

0.0056

1.32 (0.79, 2.20)

0.2895

CHARLS

 Per unit increased

852/5645 (15.09)

1.52 (1.40, 1.66)

< 0.0001

1.17 (1.00, 1.37)

0.0556

 Score = 0

255/2245 (11.36)

1 (ref)

1 (ref)

1 (ref)

1 (ref)

 Score = 1

398/2645 (15.05)

1.34 (1.15, 1.57)

0.0002

1.08 (0.82, 1.44)

0.5762

 Score = 2

164/644 (25.47)

2.47 (2.03, 3.01)

< 0.0001

1.26 (0.87, 1.83)

0.2225

 Score ≥ 3

35/111 (31.53)

3.10 (2.18, 4.41)

< 0.0001

1.99 (1.05, 3.78)

0.0346

CLHLS

 Per unit increased

2400/3259 (73.64)

1.36 (1.30, 1.42)

< 0.0001

1.19 (1.13, 1.26)

< 0.0001

 Score = 0

158/290 (54.48)

1 (ref)

1 (ref)

1 (ref)

1 (ref)

 Score = 1

604/940 (64.26)

1.28 (1.08, 1.53)

0.0054

1.04 (0.87, 1.24)

0.6928

 Score = 2

1236/1509 (81.91)

2.50 (2.12, 2.95)

< 0.0001

1.59 (1.33, 1.89)

< 0.0001

 Score ≥ 3

402/520 (77.31)

2.10 (1.74, 2.52)

< 0.0001

1.44 (1.18, 1.75)

0.0003

  1. Model 1, unadjusted; model 2, all databases were adjusted for age, gender, BMI (excluded ELSA), educational level, smoking status, vigorous exercise, depression status and number of chronic diseases.
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