Table 2 Change from baseline in WOMAC pain score, WOMAC function score and Lequesne score.

From: The comparative efficacy of L-glutamine, celecoxib, and glucosamine sulfate in osteoarthritis management

 

L-Gln

GS

CXB

Baseline

   

 No. of patients

37

33

29

 WOMAC pain score

   

  Mean ± SD

15.8 ± 6.6

15.7 ± 5.6

14.2 ± 6.8

 WOMAC function score

   

  Mean ± SD

55.4 ± 25.6

54.6 ± 17.0

49.9 ± 27.5

 Lequesne score

   

  Mean ± SD

11.2 ± 3.6

11.8 ± 3.4

9.4 ± 3.8

Week4

   

 No. of patients

37

29

27

 WOMAC pain score

   

  Change from baseline

   

   Mean ± SD

− 5.8 ± 5.1

− 5.1 ± 4.9

− 4.9 ± 5.3

   P

< 0.0001

< 0.0001

< 0.0001

   95% CI

− 7.5,− 4.1

− 7.0,− 3.3

− 7.0,− 2.8

 WOMAC function score

   

  Change from baseline

   

   Mean ± SD

− 21.1 ± 17.5

− 13.7 ± 15.6

− 16.0 ± 17.3

   P

< 0.0001

< 0.0001

< 0.0001

   95% CI

− 26.9,− 15.3

− 19.6,− 7.7

− 22.9,− 9.1

 Lequesne score

   

  Change from baseline

   

   Mean ± SD

− 2.6 ± 2.5

− 4.0 ± 3.9

− 2.6 ± 2.9

   P

< 0.0001

< 0.0001

< 0.0001

   95% CI

− 3.4, − 1.8

− 5.4, − 2.6

− 3.7, − 1.5

Week12

   

 No. of patients

37

29

27

 WOMAC pain score

   

  Change from baseline

   

   Mean ± SD

− 6.9 ± 5.1

− 6.5 ± 6.9

− 5.7 ± 5.7

   P

< 0.0001

< 0.0001

< 0.0001

   95% CI

− 8.6,− 5.2

− 9.1,− 3.8

− 8.0,− 3.4

 WOMAC function score

   

  Change from baseline

   

   Mean ± SD

− 24.9 ± 17.6

− 16.0 ± 22.0

− 19.1 ± 18.6

   P

< 0.0001

< 0.001

< 0.0001

   95% CI

− 30.7,− 19.0

− 24.4,− 7.6

− 26.5,− 11.8

 Lequesne score

   

  Change from baseline

   

   Mean ± SD

− 3.5 ± 2.3

− 4.4 ± 4.3

− 3.2 ± 3.3

   P

< 0.0001

< 0.001

< 0.0001

   95% CI

− 4.3, − 2.7

− 5.9, − 2.9

− 4.5, − 2.0

Week24

   

 No. of patients

37

29

27

 WOMAC pain score

   

  Change from baseline

   

   Mean ± SD

− 7 ± 6.1

− 5.8 ± 7.2

− 6.0 ± 6.0

   P

< 0.0001

< 0.001

< 0.0001

   95% CI

− 9.0,− 5.0

− 8.6,− 3.0

− 8.3,− 3.6

 WOMAC function score

   

  Change from baseline

   

   Mean ± SD

− 26.0 ± 19.8

− 15.4 ± 22.0

− 18.6 ± 22.5

   P

< 0.0001

< 0.001

< 0.001

   95% CI

− 32.6,− 19.4

− 23.8,− 7.0

− 27.5,− 9.7

 Lequesne score

   

  Change from baseline

   

   Mean ± SD

− 3.7 ± 2.4

− 4.1 ± 4.4

− 3.1 ± 3.6

   P

< 0.0001

< 0.001

< 0.001

   95% CI

− 4.5, − 2.8

− 5.7, − 2.6

− 4.5, − 1.7

Back to article page