Table 1 Factors Associated with Unfavorable Outcomes in DM-TB Comorbidity Cases, Brazil (2020 – 2022).
Variables | Reference Category (Value = 0) | Coefficient | p-value | OR (95% CI) |
|---|---|---|---|---|
Age 1 to 5 years | No (0) | - | - | 1.0 |
Yes | 1.0 | 0.61 | 1.18 (1.01–1.64) | |
Age 6 to 19 years | No (0) | - | - | 1.0 |
Yes | −0.46 | 0.13 | 0.63 (0.33–1.10) | |
Age 40 to 49 years | No (0) | - | - | 1.0 |
Yes | −0.45 | < 0.01 | 0.64 (0.55–0.73) | |
Age 50 to 59 years | No (0) | - | - | 1.0 |
Yes | −0.84 | < 0.01 | 0.43 (0.37–0.49) | |
Age 60 to 69 years | No (0) | - | - | 1.0 |
Yes | −1.02 | < 0.01 | 0.36 (0.30–0.42) | |
Age 70 to 79 years | No (0) | - | - | 1.0 |
Yes | −0.86 | < 0.01 | 0.42 (0.34–0.51) | |
Age 80 to 89 years | No (0) | - | - | 1.0 |
Yes | −0.74 | < 0.01 | 0.47 (0.33–0.66) | |
No (0) | - | - | 1.0 | |
Age above 90 years | Yes | −0.72 | 0.17 | 0.48 (0.14–1.22) |
Sex | Female (0) | - | - | 1.0 |
Male | 0.25 | < 0.01 | 1.28 (1.15–1.43) | |
Pregnant | No (0) | - | - | 1.0 |
Yes | 0.68 | 0.06 | 1.96 (0.98–3.63) | |
White race/color | No (0) | - | - | 1.0 |
Yes | −0.11 | 0.06 | 0.89 (0.79–1.01) | |
Black race/color | No (0) | - | - | 1.0 |
Yes | 0.15 | 0.04 | 1.15 (1.01–1.32) | |
Yellow race/color | No (0) | - | - | 1.0 |
Yes | −0.78 | 0.02 | 0.45 (0.22–0.82) | |
Brown Race/Color | No (0) | - | - | 1.0 |
0.45 | 0.88 | 1.96 (1.82—2.01) | ||
Indigenous | No (0) | - | - | 1.0 |
Yes | 0.89 | 0.21 | 1.2 (1.1- 1.6) | |
No schooling | Yes (0) | - | - | 1.0 |
No | −0.11 | 0.04 | 0.89 (0.80–0.99) | |
Complete high school | No (0) | - | - | 1.0 |
Yes | −0.32 | < 0.01 | 0.72 (0.61–0.86) | |
Complete higher education | No (0) | - | - | 1.0 |
Yes | −0.38 | 0.02 | 0.68 (0.49–0.92) | |
Incomplete higher education | No (0) | - | - | 1.0 |
Yes | −0.36 | 0.04 | 0.70 (0.48–0.98) | |
TB discovered post-mortem | No (0) | - | - | 1.0 |
Yes | −13.51 | 0.92 | 0.00 (0.00–9.99) | |
TB relapse | No (0) | - | - | 1.0 |
Yes | 0.38 | < 0.01 | 1.45 (1.21–1.74) | |
TB relapse post-abandonment | No (0) | - | - | 1.0 |
Yes | 1.33 | < 0.01 | 3.77 (3.24–4.38) | |
Alcoholism | No (0) | - | - | 1.0 |
Yes | 0.22 | < 0.01 | 1.24 (1.09–1.42) | |
Mental illness | No (0) | - | - | 1.0 |
Yes | 0.20 | 0.06 | 1.22 (0.99–1.50) | |
HIV positive | No (0) | - | - | 1.0 |
Yes | 0.66 | < 0.01 | 1.93 (1.56–2.39) | |
Positive histopathology | No (0) | - | - | 1.0 |
Yes | −0.26 | < 0.01 | 0.77 (0.65–0.89) | |
Directly Observed Treatment (DOT) | No (0) | - | - | 1.0 |
Yes | −1.09 | < 0.01 | 0.33 (0.29–0.38) | |
Incarcerated | No (0) | - | - | 1.0 |
Yes | −0.50 | < 0.01 | 0.60 (0.42–0.84) | |
Homeless | No (0) | - | - | 1.0 |
Yes | 0.86 | < 0.01 | 2.35 (1.77–3.11) | |
Immigrant | No (0) | - | - | 1.0 |
Yes | 0.76 | 0.02 | 2.13 (1.07–3.93) | |
No (0) | - | - | 1.0 | |
Government beneficiary | Yes | 0.26 | < 0.01 | 1.30 (1.10–1.52) |
Illicit drug use | No (0) | - | - | 1.0 |
Yes | 0.63 | < 0.01 | 1.87 (1.58–2.22) | |
Smoking | No (0) | - | - | 1.0 |
Yes | 0.20 | < 0.01 | 1.21 (1.08–1.37) | |
Diagnosis by TRM-TB (Tuberculosis Rapid molecular test) | No (0) | - | - | 1.0 |
Yes | −1.01 | < 0.01 | 0.36 (0.20–0.60) | |
Isoniazid resistance | Yes (0) | - | - | 1.0 |
No | −2.64 | 0.01 | 0.07 (0.01–0.32) | |
Isoniazid and rifampicin resistance | Yes (0) | - | - | 1.0 |
No | −2.51 | 0.02 | 0.08 (0.01–0.43) | |
Resistance to other drugs | Yes (0) | - | - | 1.0 |
No | −1.11 | 0.13 | 0.32 (0.05–1.09) |
