Table 1 Factors associated with stroke recurrence in MIS: univariate and multivariate Cox regression analyses.
From: The PLANS model predicts recurrent strokes in patients with minor ischemic strokes
Variable | RS | Non-RS | Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|---|---|---|
(n = 32) | (n = 186) | HR | 95% CI | P value | HR | 95% CI | P value | ||
Age (median, IQR) | 64, 51–71 | 64, 54–73 | 0.993 | 0.965–1.023 | 0.658 | ||||
Sex, female, n (%) | Female vs male | 8 (25.0) | 50 (26.9) | 0.940 | 0.422–2.092 | 0.879 | |||
BMI, (median, IQR) | 22.9, 21.6–24.8 | 22.9, 22.0–24.5 | 0.977 | 0.871–1.096 | 0.695 | ||||
Drinking, n (%) | Yes vs no | 4 (12.5) | 21 (11.3) | 1.079 | 0.378–3.075 | 0.887 | |||
Smoking, n (%) | Yes vs no | 16 (50.0) | 52 (28.0) | 2.282 | 1.141–4.564 | 0.005 | 2.793 | 1.359–5.741 | 0.005 |
Education, n (%) | 0.902 | ||||||||
Primary vs illiterate | 9 (28.1) | 64 (34.4) | 0.623 | 0.079–4.919 | 0.654 | ||||
Secondary vs illiterate | 21 (65.6) | 110 (59.1) | 0.802 | 0.108–5.963 | 0.829 | ||||
University or above vs illiterate | 1 (3.1) | 8 (4.3) | 0.553 | 0.035–8.835 | 0.675 | ||||
Living alone, n (%) | Yes vs no | 1 (3.1) | 2 (1.1) | 2.934 | 0.400–21.510 | 0.290 | |||
Admission NIHSS score | 2, 2–3 | 2, 1–3 | 2.387 | 1.432–3.978 | 0.001 | 3.092 | 1.781–5.368 | < 0.001 | |
Hypertension, n (%) | Yes vs no | 24 (75.0) | 132 (71.0) | 1.234 | 0.554–2.746 | 0.607 | |||
Diabetes, n (%) | Yes vs no | 14 (43.8) | 60 (32.3) | 1.576 | 0.784–3.168 | 0.202 | |||
Coronary heart disease, n (%) | Yes vs no | 3 (9.4) | 6 (3.2) | 2.564 | 0.781–8.418 | 0.121 | |||
Dyslipidemia, n (%) | Yes vs no | 17 (53.1) | 81 (43.5) | 1.412 | 0.705–2.828 | 0.330 | |||
Culprit vessel, n (%) | 0.705 | ||||||||
Total posterior vs Total anterior | 9 (28.1) | 38 (20.4) | 1.389 | 0.643–3.002 | 0.403 | ||||
partial anterior and posterior AIS vs Total anterior | 0 (0) | 8 (4.3) | < 0.001 | < 0.001–1.097E + 306 | 0.974 | ||||
TOAST subtype (Large artery atherosclerosis) , n (%) | Yes vs no | 23 (71.9) | 89 (47.8) | 2.590 | 1.198–5.599 | 0.016 | 2.603 | 1.189–5.701 | 0.017 |
Antiaggregants (antiplatelet), n (%) | Yes vs no | 30 (93.8) | 164 (88.2) | 1.966 | 0.470–8.227 | 0.355 | |||
Cholesterol-reducer, n (%) | Yes vs no | 31 (96.9) | 159 (85.5) | 4.905 | 0.670–35.932 | 0.118 | |||
Antidiabetic agents, n (%) | Yes vs no | 13 (40.6) | 56 (30.1) | 1.525 | 0.753–3.088 | 0.241 | |||
Antihypertensive agents, n (%) | Yes vs no | 23 (71.9) | 124 (66.7) | 1.265 | 0.585–2.735 | 0.550 | |||
Light diet, n (%) | Yes vs no | 29 (90.6) | 178 (95.7) | 0.474 | 0.144–1.557 | 0.219 | |||
Daily fresh fruit use, n (%) | Yes vs no | 16 (50.0) | 128 (68.8) | 0.492 | 0.246–0.983 | 0.045 | |||
Good sleep quality, n (%) | Yes vs no | 26 (81.3) | 161 (86.6) | 0.720 | 0.296–1.749 | 0.468 | |||
Physical activity, n (%) | < 0.001 | 0.001 | |||||||
Housework or exercise vs no | 11 (34.4) | 80 (43.0) | 0.260 | 0.112–0.599 | 0.002 | 0.248 | 0.106–0.584 | 0.001 | |
Housework and exercise vs no | 10 (31.3) | 89 (47.8) | 0.210 | 0.089–0.495 | < 0.001 | 0.170 | 0.070–0.411 | < 0.001 | |
Essen Stroke Risk Score, (median, IQR) | 2, 1–3 | 2, 1–3 | 1.253 | 0.931–1.685 | 0.136 | ||||
