Table 3 Alterations in the cut-off values of serum LRG and CRP for evaluating endoscopic moderate activity (SES-CD ≥ 7, n = 364).

From: Leucine-rich Alpha-2 glycoprotein could be clinically useful in active and postoperative Crohn’s disease

 

Cut-off value

Sensitivity

Specificity

PPV

NPV

Accuracy

LRG (µg/mL)

20.1

0.74

0.88

0.80

0.84

0.82

18.0

0.77

0.83

0.74

0.85

0.80

16.0

0.80

0.78

0.70

0.86

0.79

14.0

0.85

0.66

0.61

0.87

0.73

12.0

0.92

0.42

0.51

0.89

0.62

10.0

0.98

0.23

0.45

0.94

0.52

8.0

0.99

0.09

0.41

0.95

0.44

CRP (mg/d)

0.20

0.66

0.81

0.69

0.79

0.75

0.11

0.76

0.72

0.64

0.82

0.74

0.04

0.85

0.53

0.54

0.85

0.66

  1. SES-CD, Simplified Endoscopic Score for Crohn’s disease; LRG, leucine-rich alpha-2 glycoprotein; CRP, C-reactive protein; PPV, positive predictive value; NPV, negative predictive value.
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