Table 3 Baseline characteristics of patients with moderate to severe OHSS group and non-OHSS.
Variables | Non-OHSS group (n = 4087) | Moderate to severe OHSS group (n = 117) | Statistic | P |
|---|---|---|---|---|
Maternal age, year | 31.00 (28.00, 35.00) | 30.00 (27.00, 32.00) | Z = − 4.57 | < 0.001 |
Paternal age, year | 32.00 (29.00, 36.00) | 30.00 (29.00, 34.00) | Z = − 3.22 | 0.001 |
Body mass index, kg/m2 | 23.40 (21.10, 26.10) | 22.60 (20.70, 24.80) | Z = − 2.57 | 0.01 |
Antral follicle count | 22.00 (15.00, 28.00) | 30.00 (23.00, 40.00) | Z = − 8.08 | < 0.001 |
AMH, pmol/L | 3.65 (2.26, 5.81) | 8.98 (5.86, 13.27) | Z = − 11.42 | < 0.001 |
Basal E2, ng/L | 40.00 (27.60, 60.00) | 44.00 (31.50, 72.44) | Z = − 1.74 | 0.082 |
Basal FSH, IU/L | 6.53 (5.26, 7.99) | 5.83 (4.74, 7.07) | Z = − 3.63 | < 0.001 |
Basal LH, IU/L | 4.14 (2.74, 6.15) | 5.56 (3.50, 8.31) | Z = − 4.21 | < 0.001 |
Basal P, ng/L | 0.57 (0.34, 0.87) | 0.61 (0.42, 0.94) | Z = − 1.73 | 0.083 |
Duration of infertility, year | 3.00 (2.00, 5.50) | 3.00 (2.00, 5.00) | Z = − 0.75 | 0.453 |
LH on the day of hCG injection, IU/L | 0.93 (0.61, 1.40) | 0.89 (0.58, 1.33) | Z = − 0.95 | 0.342 |
E2 on the day of hCG injection, ng/L | 2788.00 (1600.00, 4407.00) | 5632.00 (4022.00, 7573.00) | Z = − 10.52 | < 0.001 |
P on the day of hCG injection, ng/L | 0.89 (0.57, 1.28) | 1.27 (0.89, 1.87) | Z = − 6.93 | < 0.001 |
Endometrial thickness on the day of hCG injection, mm | 11.20 (9.90, 13.00) | 11.00 (10.00, 12.43) | Z = − 0.71 | 0.477 |
Total Gn dosage, IU/L | 2625.00 (2175.00, 3300.00) | 2225.00 (1800.00, 2800.00) | Z = − 5.26 | < 0.001 |
Days of stimulation, day | 11.00 (10.00, 13.00) | 11.00 (10.00, 12.00) | Z = − 1.50 | 0.133 |
Starting dosage of Gn, IU/L | 225.00 (200.00, 225.00) | 225.00 (200.00, 225.00) | Z = − 1.29 | 0.196 |
No. of oocytes retrieved | 14.00 (9.00, 20.00) | 14.00 (10.00, 21.00) | Z = − 0.47 | 0.638 |
Hypothyroidism, % | χ2 = 50.47 | < 0.001 | ||
NO | 89.85 (3672/4087) | 69.23 (81/117) | ||
YES | 10.15 (415/4087) | 30.77 (36/117) | ||
PCOS, % | χ2 = 29.47 | < 0.001 | ||
NO | 84.49 (3453/4087) | 65.81 (77/117) | ||
YES | 15.51 (634/4087) | 34.19 (40/117) | ||
Type of infertility, % | χ2 = 12.03 | < 0.001 | ||
Primary infertility | 41.23 (1685/4087) | 57.26 (67/117) | ||
Secondary infertility | 58.77 (2402/4087) | 42.74 (50/117) | ||
Methods of ART, % | χ2 = 1.83 | 0.176 | ||
ICSI | 28.82 (1177/4087) | 23.08 (27/117) | ||
IVF | 71.18 (2907/4087) | 76.92 (90/117) |