Table 4 The univariate and multivariate analysis related to moderate to severe OHSS.
Variables | Univariate logistic regression analysis | Multivariate logistic regression analysis | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
β | S.E | Z/χ2 | P | OR (95%CI) | β | S.E | Z/χ2 | P | OR (95%CI) | |
Maternal age | − 0.09 | 0.02 | − 3.53 | < 0.001 | 0.92 (0.87–0.96) | − 0.02 | 0.04 | − 0.49 | 0.621 | 0.98 (0.90–1.07) |
Paternal age | − 0.06 | 0.02 | − 2.62 | 0.009 | 0.94 (0.90–0.98) | 0.03 | 0.04 | 0.78 | 0.433 | 1.03 (0.96–1.11) |
Body mass index | − 0.05 | 0.03 | − 1.58 | 0.113 | 0.95 (0.89–1.01) | |||||
Antral follicle count | 0.07 | 0.01 | 7.77 | < 0.001 | 1.07 (1.05–1.09) | 0.04 | 0.01 | 3.17 | 0.002 | 1.04 (1.02–1.07) |
AMH | 0 | 0 | 0.78 | 0.436 | 1.00 (1.00–1.00) | |||||
Basal E2 | 0 | 0 | − 0.57 | 0.571 | 1.00 (1.00–1.00) | |||||
Basal FSH | − 0.1 | 0.05 | − 2.05 | 0.041 | 0.90 (0.82–0.99) | − 0.03 | 0.06 | − 0.52 | 0.6 | 0.97 (0.86–1.09) |
Basal LH | 0.03 | 0.01 | 2.43 | 0.015 | 1.03 (1.01–1.05) | 0.01 | 0.02 | 0.28 | 0.781 | 1.01 (0.97– 1.05) |
Basal P | − 0.06 | 0.08 | − 0.77 | 0.439 | 0.94 (0.81–1.10) | |||||
Duration of infertility | − 0.06 | 0.04 | − 1.44 | 0.149 | 0.94 (0.86–1.02) | |||||
LH on the day of hCG injection | − 0.04 | 0.11 | − 0.36 | 0.721 | 0.96 (0.78–1.19) | |||||
E2 on the day of hCG injection | 0.01 | 0 | 9.61 | < 0.001 | 1.01 (1.01–1.01) | 0.01 | 0 | 6.28 | < 0.001 | 1.01 (1.01–1.01) |
P on the day of hCG injection | 0.22 | 0.1 | 2.26 | 0.024 | 1.25 (1.03–1.51) | 0.17 | 0.07 | 2.55 | 0.011 | 1.18 (1.04–1.34) |
Endometrial thickness on the day of hCG injection | − 0.06 | 0.05 | − 1.41 | 0.159 | 0.94 (0.86–1.03) | |||||
Total Gn dosage | − 0.01 | 0 | − 3.28 | 0.001 | 0.99 (0.99–0.99) | 0 | 0 | − 1.43 | 0.152 | 1.00 (1.00–1.00) |
Days of stimulation | − 0.09 | 0.05 | − 1.72 | 0.085 | 0.92 (0.83–1.01) | |||||
Starting dosage of Gn | 0 | 0 | − 1.25 | 0.21 | 1.00 (0.99–1.00) | |||||
No. of oocytes retrieved | 0.01 | 0.01 | 0.84 | 0.401 | 1.01 (0.99–1.03) | |||||
Hypothyroidism | ||||||||||
NO | 1.00 (Reference) | 1.00 (Reference) | ||||||||
YES | 1.29 | 0.25 | 5.12 | < 0.001 | 3.62 (2.21–5.92) | 1.29 | 0.28 | 4.64 | < 0.001 | 3.62 (2.10–6.23) |
PCOS | ||||||||||
NO | 1.00 (Reference) | 1.00 (Reference) | ||||||||
YES | 1.03 | 0.24 | 4.27 | < 0.001 | 2.81 (1.75–4.52) | 0.3 | 0.3 | 0.98 | 0.326 | 1.35 (0.74–2.43) |
Type of infertility | ||||||||||
Primary infertility | 1.00 (Reference) | 1.00 (Reference) | ||||||||
Secondary infertility | − 0.65 | 0.23 | − 2.85 | 0.004 | 0.52 (0.33–0.82) | − 0.52 | 0.27 | − 1.97 | 0.048 | 0.59 (0.35– 0.99) |
Methods of ART | ||||||||||
ICSI | 1.00 (Reference) | |||||||||
IVF | 0.35 | 0.27 | 1.27 | 0.202 | 1.41 (0.83–2.40) | |||||