Fig. 4
From: Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity

(A) Enlarged view of the binding interface of IGF-1R (grey and pink) bound to IGF-1 (blue); (B) The percentage of simulation time during which intermolecular contacts were retained between IGF-1R and IGF-1 interacting residues. Results from three simulation runs of each system are plotted as mean ± SEM.