Table 2 Comparison of sociodemographic characteristics, lifestyle, and disease history between clear cell RCC patients and non-RCC controls.

From: Interaction of tissue inhibitor of metalloproteinase 3 gene polymorphism, blood cadmium and total urinary arsenic levels on clear cell renal cell carcinoma

Variables

Clear cell RCC cases

(N = 281)

Controls

(N = 689)

Age-gender adjusted

ORs (95% CI)

Age

58.78 (49.00, 69.00)

59.00 (51.00, 71.00) a

0.99 (0.98–1.00)

Gender

   

Male

185 (66.84)

442 (64.15) b

1.00

Female

96 (34.16)

247 (35.85)

0.93 (0.69–1.124)

Educational level

   

Illiterate/elementary school

63 (22.42)

133 (19.36) b, *

1.00§,**

Junior/senior high school

105 (37.37)

231 (33.62)

0.85 (0.57–1.26)

College and above

113 (40.21)

323 (47.02)

0.60 (0.40–0.91)*

College and above vs. high school and below

  

0.67 (0.44–0.91)*

Cumulative cigarette smoking (pack year)

0.00 (0.00, 16.75)

0.00 (0.00, 6.00) a,+

1.01 (1.00–1.02)*

Alcohol consumption

   

Never

214 (76.16)

410 (59.51) b, ***

1.00§,***

Frequently

53 (18.86)

115 (16.69)

0.77 (0.53–1.13)

Occasional

14 (4.98)

164 (23.80)

0.15 (0.08–0.26)***

Frequently and Occasional

67 (23.84)

279 (40.49)

0.40 (0.29–0.56)***

Coffee consumption

   

Never

183 (65.36)

322 (46.74) b, ***

1.00§,***

Frequently

74 (26.43)

180 (26.12)

0.70 (0.50–0.97)*

Occasional

23 (8.21)

187 (27.14)

0.22 (0.14–0.35)***

Frequently and Occasional

97 (34.64)

367 (43.26)

0.45 (0.34–0.61)***

Tea consumption

   

Never

144 (51.43)

229 (33.24) b, ***

1.00§,***

Frequently

113 (40.36)

283 (41.07)

0.61 (0.45–0.83)**

Occasional

23 (8.21)

177 (25.69)

0.21 (0.13–0.33)***

Frequently and Occasional

136 (48.57)

460 (66.76)

0.45 (0.34–0.60)***

Diabetes

   

No

222 (79.29)

632 (92.13) b, ***

1.00

Yes

58 (20.71)

54 (7.87)

3.30 (2.20–4.97)***

Hypertension

   

No

150 (53.58)

514 (74.93) b, ***

1.00

Yes

131 (46.62)

172 (25.07)

2.93 (2.16–3.97)***

  1. Clear cell RCC, Clear cell renal cell carcinoma;
  2. Values are expressed as median (first quartile, third quartile) or number (%) of cases and controls.
  3. Two participants were missing for educational level; three missing for diabetes and hypertension. There were 19 missing for cumulative cigarette smoking in controls, and four missing for cumulative cigarette smoking in clear cell RCC cases.
  4. aWilcoxon rank-sum test.
  5. bχ2 test.
  6. +0.05 < p < 0.1, *p < 0.05, **p < 0.01, ***p < 0.001.
  7. § trend test,