Table 6 Stepwise multiple logistic regression analysis.

From: Interaction of tissue inhibitor of metalloproteinase 3 gene polymorphism, blood cadmium and total urinary arsenic levels on clear cell renal cell carcinoma

Variables

OR (95% CI) for clear cell RCC

Age (1 age increment)

0.98 (0.97–0.99)*

Sex (Female vs. male)

0.62 (0.40–0.95) *

Concentrations of blood cadmium (1 µg/L increment)

1.19 (1.08–1.32)***

Alcohol consumption (Frequently and Occasional vs. never)

0.47 (0.30–0.74)**

Tea consumption (Frequently and Occasional vs. never)

0.61 (0.41–0.90)*

TIMP3 rs715572 (AA vs. GG/GA)

2.12 (1.23–3.66)**

Diabetes

2.93 (1.74–4.94)***

Hypertension

2.96 (1.97–4.44)***

  1. TIMP3, tissue inhibitor of metalloproteinase 3; clear cell RCC, clear cell renal cell carcinoma.
  2. Variables included age; sex; concentrations of blood lead and cadmium and total urinary arsenic; alcohol, tea and coffee consumption; educational level; TIMP3 rs9609643 genotype; TIMP3 rs715572 genotype; and disease histories of diabetes and hypertension in the stepwise multiple logistic regression model.
  3. * p < 0.05, ** p < 0.01, *** p < 0.001.
Back to article page